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Medically Reviewed By

Dr. Srinivas

MBBS, DCP, DNB Pathology

Pathology · Last reviewed: June 2026

DENGUE ANTIBODY IGG&IGM ELISA

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About this test

The Dengue Antibody IgG & IgM ELISA Test is a laboratory blood test used to detect antibodies produced by the immune system in response to infection with the dengue virus. Dengue is a mosquito-borne viral illness transmitted primarily by the Aedes aegypti mosquito and is common in tropical and subtropical regions. Early and accurate diagnosis is essential for proper medical management and reducing the risk of severe complications such as Dengue Hemorrhagic Fever (DHF) and Dengue Shock Syndrome (DSS).

This ELISA (Enzyme-Linked Immunosorbent Assay) test measures two types of antibodies:

  • Dengue IgM Antibodies – Usually appear within 4–7 days after symptoms begin and suggest a recent or current dengue infection.
  • Dengue IgG Antibodies – Develop later and remain in the body for years, indicating a past infection or a secondary dengue infection when detected alongside IgM.

The combination of IgG and IgM results helps physicians understand the stage of infection and distinguish between primary and secondary dengue infections. Since secondary dengue infections may carry a higher risk of severe disease, this information is clinically important.

Doctors often recommend this test for patients experiencing symptoms such as high fever, severe headache, pain behind the eyes, muscle and joint pain, skin rash, nausea, vomiting, or unexplained bleeding tendencies, particularly during dengue outbreaks or after mosquito exposure.

Benefits of the Test

  • Detects both recent and previous dengue virus infections.
  • Helps differentiate primary and secondary dengue infections.
  • Supports timely diagnosis and medical treatment.
  • Assists doctors in monitoring disease progression.
  • Useful when NS1 antigen testing is no longer positive.
  • Reliable ELISA-based laboratory method.
  • Helps reduce the risk of severe dengue complications through early diagnosis.
  • Supports clinical decision-making during dengue outbreaks.

Why Doctors Recommend This Test

Doctors recommend the Dengue Antibody IgG & IgM ELISA Test when dengue infection is suspected based on symptoms, travel history, or local outbreaks. It is especially useful after the first few days of illness, when antibody production begins. The test also helps identify previous exposure to dengue virus and distinguish between primary and secondary infections, which is important for assessing the risk of severe disease.

This test may be ordered along with Dengue NS1 Antigen, Complete Blood Count (CBC), and platelet count to provide a comprehensive evaluation of dengue infection.

Preparation Before the Test

No special preparation is required.

You can eat and drink normally unless your doctor advises otherwise. Inform your healthcare provider about your symptoms, the day your fever started, recent travel history, medications, or any previous dengue infection. A blood sample is collected from a vein for laboratory analysis.

Normal Reporting Time

Typically: 1–2 Working Days

Reporting time may vary depending on laboratory workflow.

Who Should Take This Test?

This test is recommended for:

  • Individuals with suspected dengue fever.
  • Patients with high fever lasting several days.
  • People with severe headache or pain behind the eyes.
  • Individuals with muscle and joint pain.
  • Patients with skin rash or unexplained bleeding.
  • People living in or returning from dengue-endemic areas.
  • Individuals during dengue outbreaks.
  • Patients with suspected secondary dengue infection.
  • Individuals whose doctor recommends dengue antibody testing.
  • Patients requiring confirmation of recent or past dengue infection. 


Test FAQs

What is the Dengue Antibody IgG & IgM ELISA Test?

It is a blood test that detects IgG and IgM antibodies against the dengue virus to determine recent or past dengue infection.

What is the difference between Dengue IgG and IgM?

IgM antibodies indicate a recent or current infection, while IgG antibodies usually indicate a previous infection or may rise rapidly during a secondary dengue infection.

When should this test be performed?

The test is generally most useful after 4–5 days of symptom onset, when the body has started producing detectable antibodies.

Is fasting required before the test?

No. Fasting is not required.

How is the sample collected?

A healthcare professional collects a small blood sample from a vein in your arm.

Can this test diagnose dengue on the first day of fever?

Not usually. During the first few days of illness, the Dengue NS1 Antigen Test is often preferred because antibodies may not yet be detectable.

Can this test differentiate between primary and secondary dengue infection?

Yes. The pattern of IgG and IgM antibodies helps doctors distinguish between primary and secondary dengue infections.

How accurate is the ELISA test?

ELISA is a highly sensitive and specific laboratory method for detecting dengue antibodies when performed at the appropriate stage of infection.

Can I have dengue even if the antibody test is negative?

Yes. If the test is done too early, antibodies may not have developed yet. Your doctor may recommend repeat testing or additional tests such as NS1 antigen or PCR if clinically indicated.

What should I do if my result is positive?

Consult your doctor promptly. Your healthcare provider will interpret the results along with your symptoms, physical examination, CBC, platelet count, and other investigations to determine the appropriate treatment and follow-up.

DENGUE ANTIBODY IGG&IGM ELISA

Rs. 1600

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