Medically Reviewed By
Dr. Srinivas
Consultant Pathologist
Pathology · Last reviewed: June 2026

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ANTI PHOSPHOLIPID ANTIBODY - IGG
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About this test
The Anti-Phospholipid Antibody (IgG) Test is a specialized blood test that detects Immunoglobulin G (IgG) antibodies directed against phospholipids and phospholipid-binding proteins. These antibodies are important markers of Antiphospholipid Syndrome (APS), an autoimmune disorder characterized by an increased risk of abnormal blood clot formation and pregnancy-related complications.
Anti-Phospholipid IgG antibodies are among the most clinically significant antiphospholipid antibodies and are frequently associated with deep vein thrombosis (DVT), stroke, pulmonary embolism, recurrent miscarriages, and other pregnancy complications. The test is commonly performed as part of a comprehensive antiphospholipid antibody evaluation alongside Anti-Cardiolipin Antibodies, Anti-β2 Glycoprotein I Antibodies, and Lupus Anticoagulant testing.
Benefits of the Test
- Detects Anti-Phospholipid IgG antibodies with high accuracy.
- Helps diagnose Antiphospholipid Syndrome (APS).
- Assists in evaluating unexplained blood clotting disorders.
- Supports investigation of recurrent miscarriages and pregnancy complications.
- Helps assess autoimmune diseases associated with APS.
- Assists in treatment planning and long-term monitoring.
Why Doctors Recommend This Test
Doctors may recommend the Anti-Phospholipid Antibody IgG Test for individuals with:
- Deep vein thrombosis (DVT)
- Stroke or transient ischemic attack (TIA)
- Pulmonary embolism
- Recurrent miscarriages
- Pregnancy complications or stillbirth
- Unexplained arterial or venous thrombosis
- Low platelet count (thrombocytopenia)
- Systemic Lupus Erythematosus (SLE) or other autoimmune diseases
The test is commonly ordered with Anti-Phospholipid IgM, Anti-Cardiolipin IgG/IgM, Anti-β2 Glycoprotein I Antibodies, Lupus Anticoagulant, ANA Profile, and other autoimmune investigations.
Preparation Before Test
- No fasting is required.
- Continue routine medications unless instructed otherwise by your physician.
- Inform your healthcare provider about blood-thinning medications, autoimmune disorders, pregnancy history, and recent illnesses.
- A blood sample is collected for laboratory analysis.
Normal Reporting Time
Reporting Time: Usually 2–5 working days, depending on laboratory processing protocols.
Who Should Take This Test?
This test is recommended for:
- Individuals with suspected Antiphospholipid Syndrome (APS).
- Patients with unexplained arterial or venous thrombosis.
- Women with recurrent miscarriages or pregnancy complications.
- Individuals with Systemic Lupus Erythematosus (SLE).
- Patients with unexplained thrombocytopenia.
- Individuals referred by rheumatologists, hematologists, or obstetricians.
Patient-Friendly Summary
The Anti-Phospholipid Antibody (IgG) Test is a blood test that detects IgG antibodies associated with Antiphospholipid Syndrome (APS), an autoimmune disorder that increases the risk of blood clots and pregnancy complications. APS may lead to deep vein thrombosis, stroke, pulmonary embolism, recurrent pregnancy loss, or other clotting-related complications. The Anti-Phospholipid IgG antibody is considered one of the most clinically important markers of APS. This test helps doctors diagnose autoimmune clotting disorders, evaluate patients with unexplained thrombosis or pregnancy loss, and guide treatment decisions. It is a safe blood test that requires only a blood sample and generally does not require fasting.
Test FAQs
What is the Anti-Phospholipid Antibody (IgG) Test?
Why is this test performed?
Is fasting required before the test?
What sample is required?
What conditions can this test help diagnose?
Is this test performed with other antiphospholipid antibody tests?
Can this test help investigate recurrent pregnancy loss?
How long does it take to receive results?
Is the Anti-Phospholipid Antibody (IgG) Test safe?
What should I do if my result is positive?
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